Mrs Heather Harris
Imaging Facility Manager (Vaccinology and Cell Therapy Centre)
Department: Pathobiology & Population Sciences
Campus: Hawkshead
Research Groups: Host-Pathogen Interactions and Vaccinology, Musculoskeletal Biology, Cardiovascular and Renal Biology, Comparative Genomics, Endocrinology and Reproduction, Brain Health and Behaviour
Clinical Groups: Small Animal Diagnostic Imaging, Small Animal Internal Medicine
Research Centres: Imaging Suite
For any Flow Cytometry requirements and training, both analysis and sorting, or for access and training to the fluorescence microscope, please feel free to contact me
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LEPTIMMUNHOST
Leptospirosis is a zoonotic disease due to motile Spirochete bacteria. All vertebrates can be infected with pathogenic Leptospira species, such as Leptospira interrogans (L.i) that is responsible for the more severe forms of disease. Different mammals present various disease symptoms and susceptibility, which is puzzling and not understood. For example, rats and mice are asymptomatic renal carriers of leptospires, cattle suffer morbidity and abortions, whereas humans and hamsters can die from acute leptospirosis. Prevalence of leptospirosis is high in tropical and subtropical areas, and in low-income countries with poor sanitation, where seasonal rains and global warming favor the dissemination of leptospires via contaminated sewage. Despite its health and economic burden, leptospirosis is a reemerging neglected disease, but it is not even cited as such by the WHO.
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SweetAnimals
The SweetAnimal project studies the presence of sugar-binding receptors in the genomes of a variety of farmed animals, how these differ between species, what ligands expressed on pathogens they bind, and how this information can be used to develop carbohydrate-based vaccines.