91°µÍø

Amoasii L, Hildyard JCW, Li H, Sanchez-Ortiz E, Mireault A, Caballero D, Harron R, Stathopoulou TR, Massey C, Shelton JM, Bassel-Duby R, Piercy RJ, Olson  EN. Gene editing restores dystrophin expression in a canine model of Duchenne muscular dystrophy. Science. 2018 Aug 30. pii: eaau1549. doi: 10.1126/science.aau1549.

González Medina S, Hyde C, Lovera I, Piercy RJ. Detection of equine atypical myopathy-associated hypoglycin A in plant material: Optimisation and validation of a novel LC-MS based method without derivatisation. PLoS One. 2018 Jul 3;13(7):e0199521. doi: 10.1371/journal.pone.0199521.

Draper ACE, Piercy RJ. Pathological classification of equine recurrent laryngeal neuropathy. J Vet Intern Med. 2018 Jul;32(4):1397-1409. doi: 10.1111/jvim.15142. Epub 2018 Apr 24. Review. 

Hildyard JCW, Taylor-Brown F, Massey C, Wells DJ, Piercy RJ. Determination of  qPCR Reference Genes Suitable for Normalizing Gene Expression in a Canine Model of Duchenne Muscular Dystrophy. J Neuromuscul Dis. 2018;5(2):177-191. doi: 10.3233/JND-170267. PubMed PMID: 29614692

González-Medina S, Ireland JL, Piercy RJ, Newton JR, Votion DM. Equine atypical myopathy in the UK: Epidemiological characteristics of cases reported from 2011 to 2015 and factors associated with survival. Equine Vet J. 2017 Apr 26

Walmsley G, Blot, S, Venner, K. Sewry, C. Laporte, J, Blondelle J, Barthelemy, I  Maurer, M, Blanchard-Gutton, N. Pilot-Storck, F, Tiret, L, Piercy, RJ. Progressive Structural Defects in Canine Centronuclear Myopathy Indicate a Role for HACD1 in Maintaining Skeletal Muscle Membrane Systems. American Journal of Pathology. 2017 Feb;187(2):441-456.

Maile, CA, Hingst, JR, Mahalingan, KK, O'Reilly, AO, Cleasby, M, Mickelson, JR, McCue, ME, Anderson, SM, Hurley, TD, Wojyaszewski, JF, Piercy, RJ. A highly prevalent equine glycogen storage disease is explained by constitutive activation of a mutant glycogen synthase. Biochim Biophys Acta Gen Subj 2017 Jan;1861(1 Pt A):3388-3398.  

Cheetham J, Perkins JD, Jarvis JC, Cercone M, Maw M, Hermanson JW, Mitchell LM, Piercy RJ, Ducharme NG. Effects of Functional Electrical Stimulation on Denervated Laryngeal Muscle in a Large Animal Model. Artif Organs. 2015 Oct;39(10):876-85.

Chalmers HJ, Caswell J, Perkins J, Goodwin D, Viel L, Ducharme NG, Piercy RJ. Ultrasonography detects early laryngeal muscle atrophy in an equine neurectomy model. Muscle Nerve. 2015 ;53(4):583-92

Blondelle J, Ohno Y, Gache V, Guyot S, Storck S, Blanchard-Gutton N, Barthélémy I, Walmsley G, Rahier A, Gadin S, Maurer M, Guillaud L, Prola A, Ferry A, Aubin-Houzelstein G, Demarquoy J, Relaix F, Piercy RJ, Blot S, Kihara A, Tiret L, Pilot-Storck F. HACD1, a regulator of membrane composition and fluidity, promotes myoblast fusion and skeletal muscle growth. J Mol Cell Biol. 2015 Jul 9.pii: mjv049. 

Naylor RJ, Piercy RJ. Development of a clonal equine myoblast cell line capable of terminal differentiation into mature myotubes in vitro. Am J Vet Res.  2015 Jul;76(7):608-14.

Fjordbakk CT, Revold T, Goodwin D, Piercy RJ. Histopathological assessment of intrinsic laryngeal musculature in horses with dynamic laryngeal collapse. Equine Vet J. 2014 Sep 25. doi: 10.1111/evj.12357.

Fernandez-Fuente M, Terracciano CM, Martin-Duque P, Brown SC, Vassaux G, Piercy RJ. Calcium Homeostasis in Myogenic Differentiation Factor 1 (MyoD)-Transformed, Virally-Transduced, Skin-Derived Equine Myotubes. PLoS One. 2014 Aug 22;9(8):e105971.

Fernandez-Fuente M, Martin-Dijque P, Vassaux G, Brown SC, MuntoniI F, Terracciano CM, Piercy RJ. Adenovirus-mediated expression of myogenic differentiation factor 1 (MyoD) in equine and human dermal fibroblasts enables their conversion to caffeine-sensitive myotubes. Neuromuscul Disord. 2014 Mar;24(3):250-8.

Massey CA, Walmsley GL, Gliddon TP, Piercy RJ. Vacuolar myopathy in an adult warmblood horse. Neuromuscul Disord. 2013 Jun;23(6):473-7

Naylor R, Livesey L, Schumacher J, Henke N, Massey, C, Brock K, Fernandez-Fuente M, Piercy RJ. Allele copy number and underlying pathology are associated with subclinical severity in equine type 1 polysaccharide storage myopathy (PSSM1). PLoS One. 2012; 7(7):e42317

Naylor RJ, Luis-Fuentes V, Livesey L, Mobley CB, Henke N, Brock KV, Fernandez-Fuente M, Piercy RJ Evaluation of cardiac phenotype in horses with type 1 polysaccharide storage myopathy (PSSM1) J. Vet Internal Med. Nov-Dec;26(6):1464-9

NIESSEN SJ, Fernandez-Fuente M, Mahmoud A, Campbell SC, Aldibbiat A, Huggins C, Brown AE, Holder A, Piercy RJ, Catchpole B, Shaw JA, Church DB. Novel diabetes mellitus treatment: mature canine insulin production by canine striated muscle through gene therapy. Domest Anim Endocrinol. 2012 Jul;43(1):16-25

Tulloch, L.K.., Perkins, J.D. Piercy R.J. Multiple immunofluorescent labelling enables simultaneous identification of all mature fibre types in a single equine skeletal muscle cryosection. Equine Veterinary Journal. 2011 Jul;43(4):500-3.

Isgren, C.M., Upjohn, M.M., Fernandez-Fuente M., Massey, C., Pollott G., Verheyen, K.L.P., R.J. Piercy. Epidemiology of Exertional Rhabdomyolysis Susceptibility in Standardbred Horses Reveals Associated Risk Factors and Underlying Enhanced Performance. PLOS One. 2010 Jul 14;5(7):e11594 .

Perkins, J.D., Raffetto, J., Thompson, C., Weller, R., Piercy R.J. AND PFAU, T. Three-dimensional biomechanics of simulated laryngeal abduction in horses. Am J Vet Res. 2010;71(9):1003-10 .

Naylor RJ, Perkins JD, Allen S, Aldred J, Draper E, Patterson-Kane J, Piercy RJ. Histopathology and computed tomography of age-associated degeneration of the equine temporohyoid joint. Equine Veterinary Journal. 2010;42(5):425-30

Walmsley G, Arechavala-Gomeza V, Fernandez-Fuente M, Burke MM, Nagel N, Holder A, Stanley R, Chandler K, Marks SL, Muntoni F, Shelton GD, Piercy RJ. A Duchenne Muscular Dystrophy Gene Hot Spot Mutation in Dystrophin-Deficient Cavalier King Charles Spaniels is Amenable to Exon 51 Skipping. PLoS One. 2010 Jan 13;5(1):e8647

Perkins JP, Salz RO, Schumacher J, Livesey L, Piercy RJ, Barakzai SZ.. Variability of Resting Endoscopic Grading for Assessment of Recurrent Laryngeal Neuropathy in Horses. Equine Veterinary Journal. 2009; 41, 342-346

Stanley RL., M E McCue, S J Valberg, J R Mickelson, I G Mayhew, C McGowan, C N Hahn, J C Patterson-Kane, R J Piercy. A glycogen synthase 1 mutation associated with equine polysaccharide storage myopathy and exertional rhabdomyolysis occurs in a variety of UK breeds. Equine Veterinary Journal. 2009; 41, 597-601

Stanley R, Maile C, Piercy RJ. Storage associated artefact in equine muscle biopsy specimens. Equine Veterinary Journal. Volume 41, Number 1, January 2009 , pp. 82-86(5)

Fernandez-Fuente M, E Ames, M Wagner, H Zhou, M Strom, P Zammit, J Mickelson, F Muntoni, S Brown, RJ Piercy. Assessment of the transformation of equine skin–derived fibroblasts to multinucleated skeletal myotubes following lentiviral induced expression of equine myogenic differentiation 1. Am J Vet Res 2008;69:1637–1645